Clinical Scenario: Hypertensive patient brought in by ambulance for hypertensive urgency. She's been coughing x 2 days with a recent diagnosis for pneumonia. BP 198/120, HR 130's, 10L 02 with a saturation of 92%. Hypoxia affects people with lung problems like pneumonia, edema, or atelectasis even more. These issues put extra stress on the lungs,... Continue Reading →
Update to our thrombolytic therapy exclusion criteria coming soon.
Alzheimer's disease and stroke are major health issues that often affect older adults, significantly reducing their quality of life. As people get older, the chances of developing these conditions rise, leading to problems with memory, thinking, and physical abilities. Unfortunately, with aging, stroke risk also increases. A few medications treating Alzheimer's disease have been linked... Continue Reading →
Scoring a HAT trick in Sepsis
In soccer, a hat trick happens when one player scores three goals in a single game. Now, if we switch gears to the world of clinical sepsis therapy, HAT is like a dream team of intravenous treatments: hydrocortisone at 50 mg every 6 hours, ascorbic acid (vitamin C) at a whopping 1500 mg every 6... Continue Reading →
Amyloid-related imaging abnormalities (ARIA)
Case study: Mr. J. is a 76 year old gentleman who came in with left sided weakness associated with dizziness and visual changes. He was recently started on an anti-amyloid therapies Lecanemab a few weeks back to help slow down his Alzheimer's disease progression. He is AO x 3 at baseline. He is currently a... Continue Reading →
A change of ‘shift’ dilemma
Rapid response call: 05:20 am, A rapid response was called towards the end of the shift for a 56-year-old patient in the tele department for an acute desaturation event. He had a significant PMHX of colon cancer, DM 2 and COPD. The primary RN noted that the patient was on room air prior to NGT... Continue Reading →
Antiarrhythmic Agents
A simple and easy way to remember your anti-arrhythmic agents. Mnemonics: Some Block Potassium Channels. Vaughn-Williams Classification | Class I: Sodium Channel Blockers. Class II: Beta-Blockers. Class III: Potassium Channel Blockers. Class IV: Calcium Channel Blockers. Class I Class Ia: Causes moderate degree blockage of fast sodium channels. Drugs include quinidine, procainamide, and disopyramide. Causes... Continue Reading →
RSI meds in a nutshell; a 5 minute review.
Administration of sedative followed rapidly by a paralytic. RSI was created as a response to the deleterious effects of aspiration. The technique was to decrease the amount of time that a patient’s airway was unprotected during induction. Pretreatment Agents Fentanyl: 2-10 mcg/kg; Reduces sympathetic responses, useful for patients with head injuries or myocardial ischemia. Lidocaine: Can decrease... Continue Reading →
PSH management
Paroxysmal Sympathetic Hyperactivity after acquired brain injury; overstimulation secondary to TBI Treatment strategies target the inhibition of central sympathetic output, afferent sensory input, and effector organ responses to sympathetic stimulation. adrenergic agonists | Dexmedetomidine, clonidine; used to control central and peripheral adrenergic activities non selective b-blockers | Propranolol is a lipophilic, central inhibition of catecholamine... Continue Reading →
Inderal overdose
Hey guys. Have you had your coffee? How's the migraine? We have had a day with a back to back inderal overdose case in the emergency department. This is a quick 5 minute overview of Inderal treatment and management. Overview: most commonly prescribed drugs for the treatment of various cardiac disorders, hyperthyroidism, migraine, glaucoma, and... Continue Reading →
Catecholamine Vs. Non catecholamine Vasoactive agents
Catecholamine Dopamine exerts its effects on both dopaminergic and adrenergic receptors. The meta-analysis from the Surviving Sepsis Campaign guidelines 2015 did not endorse the use of dopamine due to its association with increased mortality and arrhythmias when compared to norepinephrine. However, it may be considered as an alternative to norepinephrine in patients deemed to have... Continue Reading →